Pesquisa | BVS IEC

1.

Infant microbes and metabolites point to childhood neurodevelopmental disorders.

Ahrens, Angelica P; Hyötyläinen, Tuulia; Petrone, Joseph R; Igelström, Kajsa; George, Christian D; Garrett, Timothy J; Oresic, Matej; Triplett, Eric W; Ludvigsson, Johnny.

Cell ; 187(8): 1853-1873.e15, 2024 Apr 11.

Artigo em Inglês | MEDLINE | ID: mdl-38574728

2.

Genomic characterization of metastatic patterns from prospective clinical sequencing of 25,000 patients.

Nguyen, Bastien; Fong, Christopher; Luthra, Anisha; Smith, Shaleigh A; DiNatale, Renzo G; Nandakumar, Subhiksha; Walch, Henry; Chatila, Walid K; Madupuri, Ramyasree; Kundra, Ritika; Bielski, Craig M; Mastrogiacomo, Brooke; Donoghue, Mark T A; Boire, Adrienne; Chandarlapaty, Sarat; Ganesh, Karuna; Harding, James J; Iacobuzio-Donahue, Christine A; Razavi, Pedram; Reznik, Ed; Rudin, Charles M; Zamarin, Dmitriy; Abida, Wassim; Abou-Alfa, Ghassan K; Aghajanian, Carol; Cercek, Andrea; Chi, Ping; Feldman, Darren; Ho, Alan L; Iyer, Gopakumar; Janjigian, Yelena Y; Morris, Michael; Motzer, Robert J; O'Reilly, Eileen M; Postow, Michael A; Raj, Nitya P; Riely, Gregory J; Robson, Mark E; Rosenberg, Jonathan E; Safonov, Anton; Shoushtari, Alexander N; Tap, William; Teo, Min Yuen; Varghese, Anna M; Voss, Martin; Yaeger, Rona; Zauderer, Marjorie G; Abu-Rustum, Nadeem; Garcia-Aguilar, Julio; Bochner, Bernard.

Cell ; 185(3): 563-575.e11, 2022 02 03.

Artigo em Inglês | MEDLINE | ID: mdl-35120664

3.

Synthetic lethality-mediated precision oncology via the tumor transcriptome.

Lee, Joo Sang; Nair, Nishanth Ulhas; Dinstag, Gal; Chapman, Lesley; Chung, Youngmin; Wang, Kun; Sinha, Sanju; Cha, Hongui; Kim, Dasol; Schperberg, Alexander V; Srinivasan, Ajay; Lazar, Vladimir; Rubin, Eitan; Hwang, Sohyun; Berger, Raanan; Beker, Tuvik; Ronai, Ze'ev; Hannenhalli, Sridhar; Gilbert, Mark R; Kurzrock, Razelle; Lee, Se-Hoon; Aldape, Kenneth; Ruppin, Eytan.

Cell ; 184(9): 2487-2502.e13, 2021 04 29.

Artigo em Inglês | MEDLINE | ID: mdl-33857424

4.

Neuronal Computation Underlying Inferential Reasoning in Humans and Mice.

Barron, Helen C; Reeve, Hayley M; Koolschijn, Renée S; Perestenko, Pavel V; Shpektor, Anna; Nili, Hamed; Rothaermel, Roman; Campo-Urriza, Natalia; O'Reilly, Jill X; Bannerman, David M; Behrens, Timothy E J; Dupret, David.

Cell ; 183(1): 228-243.e21, 2020 10 01.

Artigo em Inglês | MEDLINE | ID: mdl-32946810

5.

Elevated Calprotectin and Abnormal Myeloid Cell Subsets Discriminate Severe from Mild COVID-19.

Silvin, Aymeric; Chapuis, Nicolas; Dunsmore, Garett; Goubet, Anne-Gaëlle; Dubuisson, Agathe; Derosa, Lisa; Almire, Carole; Hénon, Clémence; Kosmider, Olivier; Droin, Nathalie; Rameau, Philippe; Catelain, Cyril; Alfaro, Alexia; Dussiau, Charles; Friedrich, Chloé; Sourdeau, Elise; Marin, Nathalie; Szwebel, Tali-Anne; Cantin, Delphine; Mouthon, Luc; Borderie, Didier; Deloger, Marc; Bredel, Delphine; Mouraud, Severine; Drubay, Damien; Andrieu, Muriel; Lhonneur, Anne-Sophie; Saada, Véronique; Stoclin, Annabelle; Willekens, Christophe; Pommeret, Fanny; Griscelli, Frank; Ng, Lai Guan; Zhang, Zheng; Bost, Pierre; Amit, Ido; Barlesi, Fabrice; Marabelle, Aurélien; Pène, Frédéric; Gachot, Bertrand; André, Fabrice; Zitvogel, Laurence; Ginhoux, Florent; Fontenay, Michaela; Solary, Eric.

Cell ; 182(6): 1401-1418.e18, 2020 09 17.

Artigo em Inglês | MEDLINE | ID: mdl-32810439

6.

Longitudinal Multi-omics Reveals Subset-Specific Mechanisms Underlying Irritable Bowel Syndrome.

Mars, Ruben A T; Yang, Yi; Ward, Tonya; Houtti, Mo; Priya, Sambhawa; Lekatz, Heather R; Tang, Xiaojia; Sun, Zhifu; Kalari, Krishna R; Korem, Tal; Bhattarai, Yogesh; Zheng, Tenghao; Bar, Noam; Frost, Gary; Johnson, Abigail J; van Treuren, Will; Han, Shuo; Ordog, Tamas; Grover, Madhusudan; Sonnenburg, Justin; D'Amato, Mauro; Camilleri, Michael; Elinav, Eran; Segal, Eran; Blekhman, Ran; Farrugia, Gianrico; Swann, Jonathan R; Knights, Dan; Kashyap, Purna C.

Cell ; 182(6): 1460-1473.e17, 2020 09 17.

Artigo em Inglês | MEDLINE | ID: mdl-32916129

7.

Superior immunogenicity and effectiveness of the third compared to the second BNT162b2 vaccine dose.

Lustig, Yaniv; Gonen, Tal; Meltzer, Lilac; Gilboa, Mayan; Indenbaum, Victoria; Cohen, Carmit; Amit, Sharon; Jaber, Hanaa; Doolman, Ram; Asraf, Keren; Rubin, Carmit; Fluss, Ronen; Mendelson, Ella; Freedman, Laurence; Regev-Yochay, Gili; Kreiss, Yitshak.

Nat Immunol ; 23(6): 940-946, 2022 06.

Artigo em Inglês | MEDLINE | ID: mdl-35534723

8.

Prolonged activation of nasal immune cell populations and development of tissue-resident SARS-CoV-2-specific CD8⁺ T cell responses following COVID-19.

Roukens, Anna H E; Pothast, Cilia R; König, Marion; Huisman, Wesley; Dalebout, Tim; Tak, Tamar; Azimi, Shohreh; Kruize, Yvonne; Hagedoorn, Renate S; Zlei, Mihaela; Staal, Frank J T; de Bie, Fenna J; van Dongen, Jacques J M; Arbous, Sesmu M; Zhang, Jaimie L H; Verheij, Maaike; Prins, Corine; van der Does, Anne M; Hiemstra, Pieter S; de Vries, Jutte J C; Janse, Jacqueline J; Roestenberg, Meta; Myeni, Sebenzile K; Kikkert, Marjolein; Yazdanbakhsh, Maria; Heemskerk, Mirjam H M; Smits, Hermelijn H; Jochems, Simon P.

Nat Immunol ; 23(1): 23-32, 2022 01.

Artigo em Inglês | MEDLINE | ID: mdl-34937933

9.

Proteogenomic Analysis of Human Colon Cancer Reveals New Therapeutic Opportunities.

Vasaikar, Suhas; Huang, Chen; Wang, Xiaojing; Petyuk, Vladislav A; Savage, Sara R; Wen, Bo; Dou, Yongchao; Zhang, Yun; Shi, Zhiao; Arshad, Osama A; Gritsenko, Marina A; Zimmerman, Lisa J; McDermott, Jason E; Clauss, Therese R; Moore, Ronald J; Zhao, Rui; Monroe, Matthew E; Wang, Yi-Ting; Chambers, Matthew C; Slebos, Robbert J C; Lau, Ken S; Mo, Qianxing; Ding, Li; Ellis, Matthew; Thiagarajan, Mathangi; Kinsinger, Christopher R; Rodriguez, Henry; Smith, Richard D; Rodland, Karin D; Liebler, Daniel C; Liu, Tao; Zhang, Bing.

Cell ; 177(4): 1035-1049.e19, 2019 05 02.

Artigo em Inglês | MEDLINE | ID: mdl-31031003

10.

The multiple myeloma microenvironment is defined by an inflammatory stromal cell landscape.

de Jong, Madelon M E; Kellermayer, Zoltán; Papazian, Natalie; Tahri, Sabrin; Hofste Op Bruinink, Davine; Hoogenboezem, Remco; Sanders, Mathijs A; van de Woestijne, Pieter C; Bos, P Koen; Khandanpour, Cyrus; Vermeulen, Jessica; Moreau, Philippe; van Duin, Mark; Broijl, Annemiek; Sonneveld, Pieter; Cupedo, Tom.

Nat Immunol ; 22(6): 769-780, 2021 06.

Artigo em Inglês | MEDLINE | ID: mdl-34017122

11.

Skin and gut imprinted helper T cell subsets exhibit distinct functional phenotypes in central nervous system autoimmunity.

Hiltensperger, Michael; Beltrán, Eduardo; Kant, Ravi; Tyystjärvi, Sofia; Lepennetier, Gildas; Domínguez Moreno, Helena; Bauer, Isabel J; Grassmann, Simon; Jarosch, Sebastian; Schober, Kilian; Buchholz, Veit R; Kenet, Selin; Gasperi, Christiane; Öllinger, Rupert; Rad, Roland; Muschaweckh, Andreas; Sie, Christopher; Aly, Lilian; Knier, Benjamin; Garg, Garima; Afzali, Ali M; Gerdes, Lisa Ann; Kümpfel, Tania; Franzenburg, Sören; Kawakami, Naoto; Hemmer, Bernhard; Busch, Dirk H; Misgeld, Thomas; Dornmair, Klaus; Korn, Thomas.

Nat Immunol ; 22(7): 880-892, 2021 07.

Artigo em Inglês | MEDLINE | ID: mdl-34099917

12.

Prospecting for Planarian Pluripotency.

Rozario, Tania; Newmark, Phillip A.

Cell ; 173(7): 1566-1567, 2018 06 14.

Artigo em Inglês | MEDLINE | ID: mdl-29906442

13.

Timing the Landmark Events in the Evolution of Clear Cell Renal Cell Cancer: TRACERx Renal.

Mitchell, Thomas J; Turajlic, Samra; Rowan, Andrew; Nicol, David; Farmery, James H R; O'Brien, Tim; Martincorena, Inigo; Tarpey, Patrick; Angelopoulos, Nicos; Yates, Lucy R; Butler, Adam P; Raine, Keiran; Stewart, Grant D; Challacombe, Ben; Fernando, Archana; Lopez, Jose I; Hazell, Steve; Chandra, Ashish; Chowdhury, Simon; Rudman, Sarah; Soultati, Aspasia; Stamp, Gordon; Fotiadis, Nicos; Pickering, Lisa; Au, Lewis; Spain, Lavinia; Lynch, Joanna; Stares, Mark; Teague, Jon; Maura, Francesco; Wedge, David C; Horswell, Stuart; Chambers, Tim; Litchfield, Kevin; Xu, Hang; Stewart, Aengus; Elaidi, Reza; Oudard, Stéphane; McGranahan, Nicholas; Csabai, Istvan; Gore, Martin; Futreal, P Andrew; Larkin, James; Lynch, Andy G; Szallasi, Zoltan; Swanton, Charles; Campbell, Peter J.

Cell ; 173(3): 611-623.e17, 2018 04 19.

Artigo em Inglês | MEDLINE | ID: mdl-29656891

14.

The Evolutionary Landscape of Localized Prostate Cancers Drives Clinical Aggression.

Espiritu, Shadrielle Melijah G; Liu, Lydia Y; Rubanova, Yulia; Bhandari, Vinayak; Holgersen, Erle M; Szyca, Lesia M; Fox, Natalie S; Chua, Melvin L K; Yamaguchi, Takafumi N; Heisler, Lawrence E; Livingstone, Julie; Wintersinger, Jeff; Yousif, Fouad; Lalonde, Emilie; Rouette, Alexandre; Salcedo, Adriana; Houlahan, Kathleen E; Li, Constance H; Huang, Vincent; Fraser, Michael; van der Kwast, Theodorus; Morris, Quaid D; Bristow, Robert G; Boutros, Paul C.

Cell ; 173(4): 1003-1013.e15, 2018 05 03.

Artigo em Inglês | MEDLINE | ID: mdl-29681457

15.

Deterministic Evolutionary Trajectories Influence Primary Tumor Growth: TRACERx Renal.

Turajlic, Samra; Xu, Hang; Litchfield, Kevin; Rowan, Andrew; Horswell, Stuart; Chambers, Tim; O'Brien, Tim; Lopez, Jose I; Watkins, Thomas B K; Nicol, David; Stares, Mark; Challacombe, Ben; Hazell, Steve; Chandra, Ashish; Mitchell, Thomas J; Au, Lewis; Eichler-Jonsson, Claudia; Jabbar, Faiz; Soultati, Aspasia; Chowdhury, Simon; Rudman, Sarah; Lynch, Joanna; Fernando, Archana; Stamp, Gordon; Nye, Emma; Stewart, Aengus; Xing, Wei; Smith, Jonathan C; Escudero, Mickael; Huffman, Adam; Matthews, Nik; Elgar, Greg; Phillimore, Ben; Costa, Marta; Begum, Sharmin; Ward, Sophia; Salm, Max; Boeing, Stefan; Fisher, Rosalie; Spain, Lavinia; Navas, Carolina; Grönroos, Eva; Hobor, Sebastijan; Sharma, Sarkhara; Aurangzeb, Ismaeel; Lall, Sharanpreet; Polson, Alexander; Varia, Mary; Horsfield, Catherine; Fotiadis, Nicos.

Cell ; 173(3): 595-610.e11, 2018 04 19.

Artigo em Inglês | MEDLINE | ID: mdl-29656894

16.

Tracking Cancer Evolution Reveals Constrained Routes to Metastases: TRACERx Renal.

Turajlic, Samra; Xu, Hang; Litchfield, Kevin; Rowan, Andrew; Chambers, Tim; Lopez, Jose I; Nicol, David; O'Brien, Tim; Larkin, James; Horswell, Stuart; Stares, Mark; Au, Lewis; Jamal-Hanjani, Mariam; Challacombe, Ben; Chandra, Ashish; Hazell, Steve; Eichler-Jonsson, Claudia; Soultati, Aspasia; Chowdhury, Simon; Rudman, Sarah; Lynch, Joanna; Fernando, Archana; Stamp, Gordon; Nye, Emma; Jabbar, Faiz; Spain, Lavinia; Lall, Sharanpreet; Guarch, Rosa; Falzon, Mary; Proctor, Ian; Pickering, Lisa; Gore, Martin; Watkins, Thomas B K; Ward, Sophia; Stewart, Aengus; DiNatale, Renzo; Becerra, Maria F; Reznik, Ed; Hsieh, James J; Richmond, Todd A; Mayhew, George F; Hill, Samantha M; McNally, Catherine D; Jones, Carol; Rosenbaum, Heidi; Stanislaw, Stacey; Burgess, Daniel L; Alexander, Nelson R; Swanton, Charles.

Cell ; 173(3): 581-594.e12, 2018 04 19.

Artigo em Inglês | MEDLINE | ID: mdl-29656895

17.

The anterior chamber of the eye technology and its anatomical, optical, and immunological bases.

Yang, Shao-Nian; Shi, Yue; Berggren, Per-Olof.

Physiol Rev ; 104(3): 881-929, 2024 Jul 01.

Artigo em Inglês | MEDLINE | ID: mdl-38206586

18.

Transcriptome networks identify mechanisms of viral and nonviral asthma exacerbations in children.

Altman, Matthew C; Gill, Michelle A; Whalen, Elizabeth; Babineau, Denise C; Shao, Baomei; Liu, Andrew H; Jepson, Brett; Gruchalla, Rebecca S; O'Connor, George T; Pongracic, Jacqueline A; Kercsmar, Carolyn M; Khurana Hershey, Gurjit K; Zoratti, Edward M; Johnson, Christine C; Teach, Stephen J; Kattan, Meyer; Bacharier, Leonard B; Beigelman, Avraham; Sigelman, Steve M; Presnell, Scott; Gern, James E; Gergen, Peter J; Wheatley, Lisa M; Togias, Alkis; Busse, William W; Jackson, Daniel J.

Nat Immunol ; 20(5): 637-651, 2019 05.

Artigo em Inglês | MEDLINE | ID: mdl-30962590

19.

SDHA gain-of-function engages inflammatory mitochondrial retrograde signaling via KEAP1-Nrf2.

Burgener, Anne-Valérie; Bantug, Glenn R; Meyer, Benedikt J; Higgins, Rebecca; Ghosh, Adhideb; Bignucolo, Olivier; Ma, Eric H; Loeliger, Jordan; Unterstab, Gunhild; Geigges, Marco; Steiner, Rebekah; Enamorado, Michel; Ivanek, Robert; Hunziker, Danielle; Schmidt, Alexander; Müller-Durovic, Bojana; Grählert, Jasmin; Epple, Raja; Dimeloe, Sarah; Lötscher, Jonas; Sauder, Ursula; Ebnöther, Monika; Burger, Bettina; Heijnen, Ingmar; Martínez-Cano, Sarai; Cantoni, Nathan; Brücker, Rolf; Kahlert, Christian R; Sancho, David; Jones, Russell G; Navarini, Alexander; Recher, Mike; Hess, Christoph.

Nat Immunol ; 20(10): 1311-1321, 2019 10.

Artigo em Inglês | MEDLINE | ID: mdl-31527833

20.

Consensuses, controversies, and future directions in treatment deintensification for human papillomavirus-associated oropharyngeal cancer.

Kang, Jung Julie; Yu, Yao; Chen, Linda; Zakeri, Kaveh; Gelblum, Daphna Yael; McBride, Sean Matthew; Riaz, Nadeem; Tsai, C Jillian; Kriplani, Anuja; Hung, Tony K W; Fetten, James V; Dunn, Lara A; Ho, Alan L; Boyle, Jay O; Ganly, Ian S; Singh, Bhuvanesh; Sherman, Eric J; Pfister, David G; Wong, Richard J; Lee, Nancy Y.

CA Cancer J Clin ; 73(2): 164-197, 2023 03.

Artigo em Inglês | MEDLINE | ID: mdl-36305841

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Instituto Evandro Chagas

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